Accolate treats asthma. Take this medication on an empty stomach at least 1 hour before or 2 hours after a meal.
Accolate is a prescription medication used for prevention and chronic treatment of asthma in adults and children 5 years and older.
This medication belongs to a group of drugs called leukotriene receptor antagonists. Accolate works by blocking the actions of leukotriene, a natural substance that causes swelling and tightening of the airways.
Accolate comes in tablet form and is usually taken twice daily on an empty stomach, 1 hour before, or 2 hours after a meal.
Common side effects include headache, nausea, and diarrhea.
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Accolate Cautionary Labels
Uses of Accolate
Accolate is a prescription medication used for prevention and chronic treatment of asthma in adults and children 5 years of age and older.
Asthma is a chronic lung disease that causes airway inflammation and difficulty breathing.
Accolate Drug Class
Accolate is part of the drug class:
Side Effects of Accolate
Serious side effects have been reported with Accolate. See the "Accolate Precautions" section.
Common side effects of Accolate include:
- stomach pain
- back pain
- acid indigestion
This is not a complete list of Accolate side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effects that bother you or do not go away.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- warfarin (Coumadin, Jantoven)
- theophylline (Theo-24)
- erythromycin (Ery-Tab, Erythrocin)
- fluconazole (Diflucan)
This is not a complete list of Accolate drug interactions. Ask your doctor or pharmacist for more information.
Serious side effects have been reported with Accolate including the following:
- Liver dysfuntion. Tell your healthcare provider right away if you have some or all of the following symptoms: abdominal pain, nausea, fatigue, lethargy, pruritus, jaundice, flu-like symptoms, or loss of appetite.
- Behavior and mood-related changes. Tell your doctor right away if you have mood-related changes.
- Increase in certain white blood cells (eosinophils) and possible inflamed blood vessels throughout the body (systemic vasculitis). Rarely, this can happen in people with asthma who take Accolate. This usually, but not always, happens in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered.
If you have asthma and aspirin makes your asthma symptoms worse, continue to avoid taking aspirin or other medicines called non-steroidal anti-inflammatory drugs (NSAIDs) while taking Accolate.
Avoid taking Accolate if you have liver disease including cirrhosis.
Do not taking Accolate if you are allergic to Accolate or to any of its ingredients.
Accolate Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods.
In the case of Accolate, there are no specific foods that you must exclude from your diet, but because food can reduce the amount of Accolate that gets absorbed into your body, Accolate should be taken at least 1 hour before or 2 hours after meals.
Before using Accolate, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- Are allergic to Accolate or to any of its ingredients
- Have or have had any liver disease including cirrhosis
- Are pregnant or plan to become pregnant
- Are breastfeeding or plan to breastfeed
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Accolate and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Accolate falls into category B. There are no well-done studies that have been done in humans with Accolate. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication. Accolate should be used during pregnancy only if clearly needed.
Accolate and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed.
Accolate has been detected in human breast milk. Because of the potential for serious harm in nursing infants from Accolate, a decision should be made whether to discontinue nursing or to discontinue Accolate, taking into account the importance of the medication to the mother.
Take Accolate exactly as prescribed.
Accolate comes in tablet form and is typically taken twice per day, on an empty stomach. Take Accolate 1 hour before, or 2 hours after a meal.
If you miss a dose by several hours, skip the missed dose and take your next dose at the regular time. Do not take two doses of Accolate at the same time.
Take Accolate exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The dose of Accolate prescribed for you or your child's asthma is based on age:
- The recommended dose of Accolate in adults and children 12 years and older is 20 mg twice daily.
- The recommended dose of Accolate in children 5 through 11 years of age is 10 mg twice daily.
If you take too much Accolate, call your local Poison Control Center or seek emergency medical attention right away.
- Store Accolate at 68°F to 77°F (20°C -25°C).
- Keep Accolate tablets dry.
- Keep Accolate in a tight closed container and keep Accolate out of the light.
- Keep Accolate and all medicines out of the reach of children.